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Efficacy trials (explanatory trials) determine whether an intervention produces the expected result under ideal circumstances. Efficacy, in the health care sector, is the capacity of a given intervention under ideal or controlled conditions. The measurement of a medicine's desired effect under ideal conditions, such as in a clinical trial. Vaccine efficacy measures the percentage reduction of a disease in a clinical trial. However, a great deal needs to be done and the treaty of lisbon has improved our efficacy in this sector. Introduction to Self-Efficacy - Transforming Education from www.transformingeducation.org How to use efficacy in a sentence. Vaccine efficacy measures the percentage reduction of a disease in a clinical trial. Efficacy, in the health care sector, is the capacity of a given intervention under ideal or controlled conditions. Vaccine effectiveness measures ho